90280-13-0

  • Product Name:BisfluoroModafinil
  • Molecular Formula:C15H13F2NO2S
  • Purity:99%
  • Molecular Weight:309.337
Inquiry

Product Details;

CasNo: 90280-13-0

Molecular Formula: C15H13F2NO2S

Chinese Manufacturer Supply High Purity BisfluoroModafinil 90280-13-0 with Fast Shipping

  • Molecular Formula:C15H13F2NO2S
  • Molecular Weight:309.337
  • Melting Point:78-80 °C 
  • Boiling Point:558.7±50.0 °C(Predicted) 
  • PKA:14.82±0.40(Predicted) 
  • PSA:80.36000 
  • Density:1.397±0.06 g/cm3(Predicted) 
  • LogP:4.30360 

90280-13-0 Relevant articles

LAUFLUMIDE AND THE ENANTIOMERS THEREOF, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF

-

Paragraph 0116, (2013/11/19)

The invention relates to the molecule ha...

SARs at the monoamine transporters for a novel series of modafinil analogues

Cao, Jianjing,Prisinzano, Thomas E.,Okunola, Oluyomi M.,Kopajtic, Theresa,Shook, Matthew,Katz, Jonathan L.,Newman, Amy Hauck

supporting information; experimental part, p. 48 - 52 (2011/04/22)

A series of modafinil (1) analogues were...

90280-13-0 Process route

2-(bis(4-fluorophenyl)methylthio)acetamide
90280-20-9

2-(bis(4-fluorophenyl)methylthio)acetamide

2-((bis(4-fluorophenyl)methane)sulfinyl)acetamide
90280-13-0

2-((bis(4-fluorophenyl)methane)sulfinyl)acetamide

Conditions
Conditions Yield
With dihydrogen peroxide; acetic acid;
89%
With dihydrogen peroxide; acetic acid; In methanol; water; at 40 ℃; for 24h;
66%
4,4'-difluorobenzhydryl alcohol
365-24-2

4,4'-difluorobenzhydryl alcohol

2-((bis(4-fluorophenyl)methane)sulfinyl)acetamide
90280-13-0

2-((bis(4-fluorophenyl)methane)sulfinyl)acetamide

Conditions
Conditions Yield
Multi-step reaction with 4 steps
1: trifluoroacetic acid / 20 °C
2: potassium carbonate / acetone / 4 h / Reflux
3: methanol; ammonium hydroxide; ammonium chloride / 72 h / 50 °C
4: dihydrogen peroxide; acetic acid / methanol; water / 24 h / 40 °C
With methanol; ammonium hydroxide; dihydrogen peroxide; potassium carbonate; ammonium chloride; acetic acid; trifluoroacetic acid; In methanol; water; acetone;
 
Multi-step reaction with 3 steps
1: hydrogen bromide / water / 60 - 80 °C
2: sodium hydroxide / water / 60 °C
3: dihydrogen peroxide; acetic acid
With hydrogen bromide; dihydrogen peroxide; acetic acid; sodium hydroxide; In water;
 

90280-13-0 Upstream products

  • 90212-82-1
    90212-82-1

    methyl [[bis-(4-fluorophenyl)methyl]thio]acetate

  • 90280-20-9
    90280-20-9

    2-(bis(4-fluorophenyl)methylthio)acetamide

  • 90212-81-0
    90212-81-0

    2-((bis(4-fluorophenyl)methyl)-thio)acetic acid

  • 365-24-2
    365-24-2

    4,4'-difluorobenzhydryl alcohol

BisfluoroModafinil(Cas 90280-13-0) Usage

Description

CRL-40,940 (also known as flmodafinil, bisfluoromodafinil and lauflumide) is the bisfluoro analog of modafinil.It is a eugeroic as well as a weak dopamine reuptake inhibitor. Its inventors claim that it is more effective than modafinil and adrafinil, with fewer side effects. It was patented in 2013, and pre-clinical trials have been underway since December 2015.

Uses

It helps to enhance the mental intelligence and the motivation level. It improves brain power to solve problems and protects it from any chemical or physical injury. It can be used to treat attention deficit disorders, sleep disorders, and mild depression.

Supplier

Shandong Zhimao New Materials Co., Ltd is a high-quality supplier producing BisfluoroModafinil. The company takes the lead in the domestic leading plastic pellet production line, the production of products with good quality, stable performance and complete variety.

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